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Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Targeting TGFβ can improve skin immunity in older people.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Oxidative stress is linked to mild patchy alopecia areata.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Different sports can cause specific skin conditions that need proper diagnosis and treatment.

Leptin helps start the growth phase of hair.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.