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The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.

A group has developed therapies that show promise for treating cancer and various other conditions.

RXRα is crucial for proper immune response and links diet to immune function.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The technology can help diagnose and subtype autoimmune diseases by identifying specific autoantibodies.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Onion and Aloe vera can help protect hair from damage caused by hair dyes.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.

ILC1 cells contribute to hair loss in alopecia areata.

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

GLI2 increases follistatin production in human skin cells.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

A specific protein in chicken embryos links early skin layers to feather development.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Thyroid function affects skin health, with a complex interaction between the two.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.