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    Glossary Antiandrogenic Effects

    inhibit male sex hormones like testosterone

    Antiandrogenic effects refer to the actions of substances that inhibit the effects of androgens, which are male sex hormones like testosterone. These substances can block androgen receptors or reduce androgen production, and are often used in treatments for conditions like prostate cancer, androgenic alopecia (male-pattern baldness), and hirsutism (excessive hair growth in women).

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    1. The effect of the antiandrogen IIα-hydroxyprogesterone on sebum production and cholesterol concentration of sebum British Journal of Dermatology · 1982 · 27 citations
    2. Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy Neuroscience Letters · 2022 · 3 citations
    3. Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position Steroids · 1999 · 19 citations
    4. The Effect of Anti-Androgens on the Response of Rat Preputial Glands to Testosterone* 1964 · 16 citations
    5. The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination with Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study. PubMed · 2023
    6. Effects of Flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat Gynecological Endocrinology · 1987 · 8 citations
    7. Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb. Fitoterapia · 2012 · 44 citations
    8. Anti-Androgenic Effects of Spearmint Tea (Mentha Spicata) CommonKnowledge Research Repository (Pacific University Oregon) · 2017
    9. Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells Toxicology in Vitro · 2025 · 1 citations
    10. Anti-Androgen Effects of Extracts and Compounds from<i>Ganoderma lucidum</i> Chemistry & Biodiversity · 2009 · 20 citations
    11. Anti-proliferative effect of terpenes on human prostate cáncer cells: natural sources and their potential role as chemopreventive agents. Revista chilena de nutrición · 2017 · 3 citations
    12. Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis European Journal of Pharmacology · 2023
    13. Effects of Antiandrogen Treatment on the Sexuality of Women with Hyperandrogenism Psychotherapy and psychosomatics · 1984 · 17 citations
    14. EFFECT OF ANTIANDROGENS ON VALPROIC ACID-INDUCED NEURODEVELOPMENTAL CHANGES IN RATS 2023
    15. Effects of antiandrogen therapy of cyproteron acetate on androgen effects on the skin including androgenetic alopecia in menopausal women – case report: 10 years follow up – Endocrine Abstracts · 2022
    16. Effects of Prenatal Treatment with Antiandrogens on Luteinizing Hormone Secretion and Sex Steroid Concentrations in Adult Spotted Hyenas, Crocuta crocuta1 Biology of Reproduction · 2002 · 37 citations
    17. Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells Records of Natural Products · 2018 · 5 citations
    18. The antiandrogenic effect of finasteride against a mutant androgen receptor Cancer Biology & Therapy · 2011 · 20 citations
    19. Spearmint herbal tea has significant anti‐androgen effects in polycystic ovarian syndrome. a randomized controlled trial 2009 · 90 citations
    20. Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts Journal of the American Academy of Dermatology · 2005 · 2 citations
    21. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice British Journal of Dermatology · 1997 · 10 citations
    22. Histological and immunohistochemical examination of the effect of the nonsteroidal antiandrogen {flutamide} on some organs of the male reproductive system in albino rats The Egyptian Journal of Histology · 2012
    23. Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects Fertility and sterility · 1999 · 75 citations
    24. Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes Journal of Pharmaceutical Sciences · 1997 · 62 citations
    25. Research Brief: Self-Reports of a Constellation of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men American Journal of Men's Health · 2018 · 9 citations
    26. Connarus semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway Molecules · 2022 · 2 citations
    27. Hair Growth Promotion and Anti-Hair Loss Effects of By-Products Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction Foods · 2023
    28. Changes of sex hormone levels in male acne patients with normal serum testosterone and effect of antiandrogen therapy Academic Journal of Second Military Medical University · 2009
    29. Anti-Androgenic Potential of Plant Extracts: Molecular Mechanisms, Synergistic Effects, and Nutritional Interventions Molecules · 2026
    30. Evaluation of Derma Genie™-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects Asian journal of beauty & cosmetology · 2024