research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
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research Diagnosis and Treatments of Hirsutism: Where Are We?
Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
research Molecular Interactions of Natural and Synthetic Steroids in Female Hamsters’ Flank Organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Specific Morphogenetic Events in Mouse External Genitalia Sex Differentiation Are Dependent Upon Androgens and Estrogens
Mouse genital development depends on male or female hormones for specific features.
research Alopecia in Patients with COVID-19: A Systematic Review and Meta-Analysis
Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.
research Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Oral Bicalutamide for Female Pattern Hair Loss: A Pilot Study
Bicalutamide improves hair density in women safely.
research Spironolactone in Dermatology: Uses in Acne and Beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
research The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia
Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Shortness of Breath: An Uncommon Side-Effect of Cyproterone Acetate in the Treatment of Androgenetic Alopecia
Cyproterone acetate can cause rare shortness of breath in women.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Topical Treatment of Androgenetic Alopecia with Spironolactone
Topical spironolactone effectively treats hair loss in women.
research Female Antiandrogens: Significance, Treatment, and Environmental Concerns
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research The Pathological Dynamics of Androgenetic Alopecia and Its Treatment
Topical spironolactone effectively treats hair loss in women.
research Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone
Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
research A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women
Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond
Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Treatment of Female Pattern Hair Loss with a Combination of Spironolactone and Minoxidil
Spironolactone and minoxidil together effectively treat female pattern hair loss.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research Hair Regrowth
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review
No cure for female pattern hair loss, but various effective treatments exist.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Androgenetic Alopecia: Causes, Diagnosis, and Treatment Options
Hair loss from genetics and hormones can be treated with drugs or surgery.
research Current Treatment of Benign Prostatic Hyperplasia
TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.