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Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Polyamines help fix DNA damage accurately in cells.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

A patient with a rare form of lupus improved after treatment for skin ulcers and hair loss on the face and scalp.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.

A child with a rare scalp condition regrew hair after treatment.

Belimumab reduces disease activity, steroid use, and flares in lupus patients.

A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.

Belimumab effectively controls SLE disease activity and reduces steroid use.

Certain skin symptoms can help detect and manage systemic lupus.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.