December 2024 in “International Journal of Molecular Sciences” This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.
October 2025 in “Indian Journal of Plastic Surgery” This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.
December 2024 in “African Journal of Biomedical Research” This review discusses the potential of 3D bioprinting to revolutionize cosmetic treatments through personalized skin regeneration, facial reconstruction, and anti-aging therapies, while highlighting the current challenges and promising future in the field of cosmetology.
April 2024 in “International journal of women's health” This review explores adult female acne, focusing on its multifactorial causes, treatment options, and impact on quality of life, but reports no new clinical results.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” This review discusses the complex role of the immune system in tissue repair and regeneration, highlighting its positive and negative influences but reports no new clinical findings.
3 citations
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February 2024 in “International journal of molecular sciences” This review highlights the potential of valorizing citrus by-products, particularly hesperidin from orange peels, as sustainable ingredients in skincare for antiaging, pigmentation, wound healing, and UV damage protection, emphasizing hesperidin's role in a circular economy approach.
January 2025 in “Stem Cells International” In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.
210 citations
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May 2006 in “The FASEB journal” This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.
May 2018 in “International journal of cell science & molecular biology” This article discusses the biology of cosmetic aging and the chemical pathways involved, emphasizing research advancements that aid clinicians in rejuvenating skin and increasing scalp hair density, but it provides no new results.
August 2023 in “Theoretical and Natural Science” This review discusses the potential anti-aging effects of adipose-derived stem cells on facial skin, such as reducing wrinkles, whitening skin, and promoting hair growth, but provides no new clinical results.
2 citations
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January 2018 in “International Journal of Advanced Community Medicine” This study reported the formulation of a new cream combining niacinamide and retinol aimed at reducing hyperpigmentation and providing anti-aging and moisturizing effects. It found that the cream remained stable under various environmental conditions and did not cause skin irritation in patch tests.
1 citations
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February 2025 in “Journal of Biomedical Research & Environmental Sciences” This review explores the diverse health benefits and pharmacological properties of mushrooms, highlighting their potential use in cosmetics for antioxidant, anti-aging, and anti-hair loss effects due to their bioactive compounds.
1 citations
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August 2023 in “Bioengineering” This review explores the potential benefits of platelet-rich plasma for anti-aging and tissue regeneration, especially in orthopedic applications like osteoarthritis, but it reports no new clinical results.
September 2025 in “International Journal of Biology Pharmacy and Allied Sciences” In this review, the authors examined the bioactive compounds in rosemary, noting its potential anti-inflammatory, antimicrobial, wound-healing, and anticancer activities, and highlighted its use in traditional medicine and cosmetics for conditions such as aging, baldness, and sun damage.
February 2026 in “MedScien” This study found that mesenchymal stem cells mainly promote skin regeneration and delay aging through paracrine activity, releasing growth factors and cytokines that protect against oxidative stress and stimulate healing.
May 2026 in “Current Medicinal Chemistry” This systematic review suggests that human placental extracts may offer therapeutic benefits for non-communicable diseases such as liver pathologies and metabolic disorders, but larger trials are needed to confirm efficacy and understand molecular pathways.
13 citations
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May 2021 in “FASEB bioAdvances” This review discusses plant-based alternatives to retinoids for dermal antiaging and hair health, highlighting roles for cytokinins and phytoestrogens and reports no new results.
7 citations
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October 2024 in “Cells” This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.
1 citations
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June 2023 in “Pharmacognosy Research” This review highlights the promising therapeutic potential of Bacopa monnieri in treating various health conditions, particularly related to neuropharmacology, but emphasizes the need for further clinical research.
This source provides an overview of quercetin's therapeutic capabilities in skin wound healing, highlighting its antioxidant and anti-inflammatory benefits but noting its poor solubility limits skin penetration; various delivery strategies have been explored to enhance its effectiveness.
September 2023 in “Molecular frontiers journal” This paper highlights the growing interest in exosomes for their therapeutic and diagnostic potential in cosmetic dermatology, noting their roles in skin rejuvenation, postprocedural care, and antiaging treatments.
23 citations
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January 2025 in “Annals of Dermatology” This review highlights that air pollution can worsen inflammatory skin conditions and accelerate skin aging, with oxidative stress and skin barrier disruption being key mechanisms involved, suggesting potential roles for antioxidant and anti-inflammatory treatments.
This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.
13 citations
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October 2007 in “Bulletin of the Korean Chemical Society” This article reviews mollugin's reported biological activities, including its potential for various therapeutic and cosmetic applications such as anti-tumor effects and hair growth stimulation, but presents no new experimental data.
January 2017 in “Elsevier eBooks” This review discusses the potential of Ziziphus species and its extracted oil as new therapeutic agents in drug development and highlights the need for further studies to fully exploit this species for human health benefits.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this preprint, an integrative regenerative protocol involving microneedling, plant-derived exosomes, and other therapies was used to treat androgenetic alopecia in an elderly woman, resulting in improved hair density and scalp coverage.
October 2025 in “Editora Pasteur eBooks” The abstract discusses the multidisciplinary nature and advancement of dermatology and aesthetic procedures within the health sciences, emphasizing the integration of diagnostic, corrective, preventive, and therapeutic approaches, but does not provide specific study results.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
January 2017 in “Chemistry & Industry” Eating fewer calories may slow aging and removing old cells can increase lifespan in mice.
5 citations
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February 2025 in “Frontiers in Immunology” This study highlights emerging research on lactate's biological roles in skin health, emphasizing its function as a signaling molecule that regulates skin barrier and immunity, and notes its therapeutic potential for skin conditions such as tumors and inflammatory diseases.