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Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride can cause sexual problems and depression in young men.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Putting ketoconazole on the skin can help mice grow hair.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Topical estrogen helps hair growth in menopausal women with no major side effects.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.