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Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Hidradenitis suppurativa improves with antiandrogen therapy.

Androgens may block hair growth signals, targeting this could treat hair loss.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

DHT stops hair regrowth in mice, similar to human hair loss.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Women with greater androgen sensitivity respond better to finasteride for hair loss.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Certain gene variations might be linked to severe acne in women but not in men.

Testosterone is crucial for development, growth, and various body functions in mammals.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

No clear link between specific gene and hair loss in Mexican brothers.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.