102 citations,
June 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
98 citations,
October 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
13 citations,
July 2004 in “Skinmed” Common types of non-scarring hair loss have various causes and treatments, but more effective solutions are needed.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
32 citations,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
229 citations,
August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
7 citations,
September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
1 citations,
January 2009 in “Drug delivery system” Anti-aging treatments like hair transplants, minoxidil, and finasteride effectively promote hair growth.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
June 2006 in “Current Opinion in Endocrinology & Diabetes” Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
30 citations,
March 2010 in “European Journal of Dermatology” Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.
3 citations,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
17 citations,
August 2012 in “Archives of Pharmacal Research” Acankoreoside J from Acanthopanax koreanum may help promote hair growth.
53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
4 citations,
November 2015 in “Journal of Investigative Dermatology” Testosterone may worsen hair loss by affecting hair growth signals, while different prostaglandins can either hinder or promote hair growth.
9 citations,
March 2001 in “Clinics in dermatology” Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.
128 citations,
March 2006 in “American Journal of Pathology” Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
49 citations,
February 2019 in “The Journal of Clinical Endocrinology and Metabolism” Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
12 citations,
August 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
19 citations,
March 1996 in “British Journal of Dermatology” Balding hair follicle cells are smaller, grow less well, and need more effort to culture than non-balding cells.
30 citations,
May 2010 in “British Journal of Dermatology” Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.
39 citations,
April 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
35 citations,
March 2005 in “Journal of Investigative Dermatology” Potassium channel openers like minoxidil help hair grow by acting on hair follicles.
24 citations,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.