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    Effectiveness and Safety of Hair Growth Formulation Containing Tectona Grandis L.f (Teak) Leaf Extract: A Randomized, Double-Blind, Placebo-Controlled Study on Males with Androgenic Alopecia

    March 2024 in “ Journal of Evidence-Based Integrative Medicine ”
    Nutchaninad Tanuphol, Neti Waranuch, Vanuchawan Wisuitiprot … Kornkanok Ingkaninan
    Studysummary This study found that a hair tonic containing 1% teak leaf extract significantly increased hair growth and user satisfaction in men with androgenic alopecia after 24 weeks, without causing adverse effects, and was comparable to the standard treatment, minoxidil.
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    Research cited in this study 21

    1. Effects of Solvent System and Storage Condition on Chemical Stability of 5α-Reductase Inhibitor Compounds in Tectona Grandis Leaf Extracts Trends in Sciences · 2024
    2. The Diagnosis and Treatment of Androgenetic Alopecia: A Review of the Most Current Management Forum Dermatologicum · 2023
    3. Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    4. Prevalence of Telogen Effluvium Hair Loss in COVID-19 Patients and Its Relationship with Disease Severity Journal of medicine and life · 2022
    5. Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona Grandis Leaf Extract Molecules · 2022
    6. Relationship Between Hair Shedding and Systemic Inflammation in COVID-19 Pneumonia Annals of Medicine · 2022
    7. Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors Sexual medicine reviews · 2018
    8. A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors Medical Hypotheses · 2017
    9. Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies Archives of Dermatological Research · 2017
    10. Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors Medicinal Chemistry Research · 2017
    11. Systemic Causes of Hair Loss Annals of Medicine · 2016
    12. Androgenetic Alopecia: Modeling Progression and Regrowth Experimental Dermatology · 2016
    13. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    14. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    15. Curcuma Aeruginosa, A Novel Botanically Derived 5α-Reductase Inhibitor In The Treatment Of Male-Pattern Baldness: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Journal of Dermatological Treatment · 2011
    16. Effect of Tectona Grandis Linn. Seeds on Hair Growth Activity of Albino Mice International Journal of Ayurveda Research · 2010
    17. Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects International Journal of Trichology · 2009
    18. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002
    19. Investigation of Topical Application of Procyanidin B-2 from Apple to Identify Its Potential Use as a Hair Growing Agent Phytomedicine · 2000
    20. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    21. Fortnightly Review: Male Pattern Androgenetic Alopecia BMJ · 1998