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RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Certain gene variations might be linked to severe acne in women but not in men.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Lowering testosterone speeds up wound healing in male mice.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Androgens may block hair growth signals, targeting this could treat hair loss.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

DHT stops hair regrowth in mice, similar to human hair loss.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

DHT, a testosterone byproduct, causes male pattern baldness.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.