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Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Finasteride may cause kidney damage.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

Soy supplements improve various skin conditions and aging signs, with topical use boosting skin barrier function.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Men with Kennedy disease have less chance of hair loss.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Finasteride may reduce bleeding after TURP, but more research needed.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.