Is Androgenetic Alopecia Associated With Benign Prostatic Hyperplasia? Analysis of 907 Patients

    April 2013 in “ The Journal of Urology ”
    João Alexandre Ribeiro Gonçalves Barbosa, Eduardo Muracca, lcio Nakano, Mario Paranhos, Paulo Cordeiro, Miguel Srougi, Alberto A. Antunes
    Image of study
    TLDR Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.
    This document is a collection of abstracts from a urology journal. One study analyzed 907 patients to determine if there is an association between androgenetic alopecia (AGA) and benign prostatic hyperplasia (BPH). The study found that patients with AGA had higher log PSA and urinary symptoms more frequently than those without hair loss, most likely due to older age. Mean prostate weight was similar in both groups. Age, PSA, previous cardiovascular event, and waist-to-hip ratio were independent predictors of LUTS. Another study investigated the impact of abdominal aortic calcification (AAC) and visceral fat obesity on LUTS and clinical parameters in patients with BPH. The study found that AAC correlated with only objective parameters, while VFA correlated with only storage symptoms. The increase of visceral fat is a risk factor for storage symptoms rather than voiding symptoms. AAC and VFA affect subjective and objective parameters in patients with LUTS/BPH.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 1 year ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  26 upvotes 2 months ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  331 upvotes 10 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 1 year ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

    Similar Research

    5 / 1000+ results