235 citations
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September 2004 in “The Journal of urology/The journal of urology”
This review discusses the role of dihydrotestosterone in benign prostatic hyperplasia and reports no new results; the authors highlight 5alpha-reductase inhibitors as a well-established treatment option.
December 2023 in “Bulletin of Pharmaceutical Sciences Assiut”
In this study, GC/MS analysis revealed variability in the quality of Syrian herbal formulations for BPH, with variations in tocopherol content, presence of parabens, and shortages of certain phytosterols.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study identifies GZL626, a first-in-class degrader of the androgen receptor N-terminal domain, which may overcome resistance in advanced prostate cancer by targeting both full-length and variant receptors.
Finasteride is discussed as a hair loss treatment with benefits like reduced prostateenlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.
The conversation discusses prostate aches experienced by someone taking oral finasteride for hair loss, with users suggesting the aches may be due to prostate size reduction. Some users share similar experiences, while others express skepticism about the side effects.
The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.
The user has been using a topical solution with 6% minoxidil and 0.3% finasteride for 5 years, noticing positive results but still considering a hair transplant. Other users discuss the effectiveness of minoxidil over time, suggest alternatives like dutasteride, and mention microneedling as an additional treatment.
A user shared how they bought an 18-month supply of finasteride for $23.50 in Turkey by purchasing 5mg pills and splitting them. They also mentioned buying other medications like painkillers and antibiotics from local pharmacies.