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New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Skin aging reflects overall body aging and can indicate internal health conditions.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

A gene called HDAC9 might be a new factor in male-pattern baldness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Adding a second method to PROTACs could improve cancer treatment.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Nanoformulations improve luteolin's effectiveness as a cancer treatment.

Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.