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The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Men with more advanced male pattern baldness have a higher risk of prostate cancer and more severe disease.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Men with early hair loss may have a higher risk of enlarged prostate and possibly prostate cancer due to shared hormonal factors.

Male pattern baldness may predict prostate cancer risk.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

More prostate biopsies increase the chance of finding cancers that may not need treatment.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Gene variation affects prostate issues and hair loss.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Men with testicular cancer were less likely to experience baldness and severe acne.

Minoxidil can reduce functions related to androgen receptors.

The conclusion is that there might be a link between certain types of baldness and prostate cancer, which could be due to shared hormonal pathways.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Analog 23 is a promising compound for prostate cancer treatment.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

CT scans can find serious prostate cancer even when PSA levels are low.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

The vitamin D receptor can work without its usual activating molecule.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.