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Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Melatonin may help treat PCOS symptoms in rats.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

In Spain, dermatologists most commonly prescribe topical minoxidil and oral finasteride for male hair loss, and topical minoxidil and oral contraceptives for female hair loss. The use of oral dutasteride and oral minoxidil has significantly increased over the past three years.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Possible link between androgens and COVID-19 severity; more research needed.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

More research is needed to understand how testosterone is maintained in adult males.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.