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P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Finasteride caused blisters on hands and feet.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Liposomes could improve how skin care products work but are costly and not very stable.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Adrenal disorders can cause lasting brain and behavior issues in children.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.