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Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Both estrogens and androgens are important for health in both males and females.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

The document's conclusion cannot be provided because the document is not accessible or understandable.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Finasteride helps reduce heart issues and improves heart function.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

Kelulut Honey can help regulate sex hormone receptors in rats with Polycystic Ovary Syndrome, similar to common medications.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Lower growth factors linked to balding in androgenetic alopecia.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Finasteride helps reduce heart enlargement in heart failure patients.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.