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Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Mutations in certain receptors can cause diseases and offer new treatment options.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Different processes create patterns in skin and things like hair and feathers.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Finasteride helps treat hair loss by blocking enzyme activity.