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Hormones and genes affect hair growth and male baldness.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.

The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Androgen use may increase the risk of stroke, but more research is needed.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.