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Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Early onset hair loss linked to genetics and androgen levels.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

Women with high androgen levels may have more severe COVID-19 symptoms.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.

Higher androgen levels do not cause baldness in men.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.