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The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Teak is a durable, termite-resistant wood with medicinal benefits.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

New genes and pathways are important for testosterone production and male sexual development.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Sex hormones, especially androgens, play a key role in causing acne.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.