12 citations
,
August 2018 in “Journal of Dermatological Science” This study observed that adipose-derived stem cells modified with trichogenic factors have similar properties to dermal papilla cells and show enhanced hair regeneration potential compared to unmodified adipose-derived stem cells.
11 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.
11 citations
,
May 2015 in “Stem Cells Translational Medicine” This study found that megestrol acetate increases the proliferation, migration, and adipogenic differentiation of adipose-derived stem cells through glucocorticoid receptor phosphorylation.
9 citations
,
April 2019 in “Biomolecules & Therapeutics” This study found that udenafil-treated adipose-derived stem cells accelerated hair growth in mice by enhancing stem cell activity and growth factor secretion through the ERK and NFκB pathways.
9 citations
,
March 2011 in “Current Pharmaceutical Biotechnology” This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.
8 citations
,
June 2023 in “Journal of clinical medicine” This study reviews the use of nanofat in facial rejuvenation and cosmetic surgery, highlighting its potential for improving skin appearance and treating conditions like wrinkles and acne scars, yet emphasizes the need for further research into its long-term efficacy and safety.
8 citations
,
February 2021 in “Journal of Clinical Medicine” This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.
8 citations
,
January 2016 in “Journal of Veterinary Medical Science” This study found that canine adipose-derived mesenchymal stem cell-derived dermal papilla-like tissues promoted new hair follicle formation and increased vascularization in mice, suggesting potential for hair regeneration.
6 citations
,
May 2023 in “International journal of molecular sciences” This study supports using mesenchymal stem cells cultured with collagen to accelerate skin wound healing in mice and canines, by enhancing epidermal repair and promoting factors essential for skin recovery.
6 citations
,
April 2023 in “Cosmetics” In this review, researchers explored the potential of exosomes in cosmetics, skincare, tissue regeneration, and dermatological treatment, noting their promising ability to modulate cellular environments, potentially improving skin health and treating various skin conditions.
6 citations
,
December 2022 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel bilayer wound dressing made from PLCL nanofibers and keratin hydrogel, loaded with FGF-2, promoted skin healing and showed potential for use in skin tissue engineering.
6 citations
,
November 2020 in “Annals of Plastic Surgery” In this study, co-administering adipose-derived stem cells with platelet-rich plasma reduced radiation therapy-induced skin and hair follicle damage in mice, suggesting potential for clinical application.
4 citations
,
August 2021 in “Clinics in Dermatology” This paper reviews the potential of stem cells, especially adipose-derived ones, in cosmetic dermatology, particularly for androgenetic alopecia and skin rejuvenation, highlighting their promise but noting the need for more rigorous trials to confirm their effectiveness and standardize treatments.
4 citations
,
September 2020 in “Annals of Translational Medicine” This study found that concentrated nanofat, used alone or with decellularized nanofat, may enhance hair growth in mice by activating dermal papilla cells and the anagen phase.
3 citations
,
August 2025 in “Stem Cell Research & Therapy” This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.
3 citations
,
May 2025 in “Lasers in Surgery and Medicine” This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.
3 citations
,
September 2023 in “Skin research and technology” This review article highlights the potential of mesenchymal stem cells, their exosomes, and non-coding RNAs in repairing aging skin tissues due to their ability to secrete beneficial compounds, suggesting their promising role in photoaging treatment without causing immune rejection or granuloma formation.
3 citations
,
March 2023 in “Life” This review discusses recent findings on wound healing with a focus on adipose tissue biology and obesity, but presents no new clinical results.
3 citations
,
September 2017 in “Stem cell investigation” This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.
3 citations
,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
3 citations
,
December 2007 in “Journal of Otology” This study found that adipose-derived stem cells from adult guinea pigs can differentiate into hair cell-like cells in vitro, suggesting potential use in tissue engineering.
2 citations
,
September 2025 in “Journal of Clinical Medicine” This review highlights the potential of regenerative medicine therapies, such as biologics and emerging technologies, to significantly impact aesthetic and reconstructive procedures in plastic surgery and dermatology.
2 citations
,
January 2025 in “动物学研究” In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.
2 citations
,
February 2024 in “Toxins” This study found that bee venom accelerated the transition from the telogen to anagen phase in mice, increasing hair growth by day 14, and suggested that bee venom may enhance adipose-derived stem cell activity by upregulating growth factor secretion.
2 citations
,
December 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses the development and potential applications of organoids for human disease modeling and regenerative medicine but reports no new experimental results.
2 citations
,
October 2022 in “Journal of Biomedical Science” This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.
2 citations
,
September 2022 in “Cytotherapy” This review summarizes recent research on the therapeutic uses of adipose-derived stem cells for wound healing and treating skin diseases but does not provide new experimental results.
2 citations
,
June 2022 in “Cosmoderma” This review discusses regenerative medicine's applications in dermatology, highlighting the need for quality clinical trials to optimize treatments like PRP, stem cells, and exosomes, and reports no new results.
2 citations
,
May 2020 in “Research Square (Research Square)” The researchers reported that adipose-derived stem cells from type 2 diabetic mice showed comparable therapeutic effects in wound healing to control cells, despite slightly reduced growth factor secretion and healing promotion.
2 citations
,
May 2017 in “InTech eBooks” This review discusses the regenerative potential of hair follicle stem cell populations and current approaches to reconstructing folliculogenesis for alopecia therapy, but reports no new clinical results.