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Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Consider necrolytic acral erythema in similar cases and treat with oral zinc sulfate.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

High doses of tryptophan may cause eosinophilic fasciitis.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

SCD1 is crucial for skin health and overall energy balance.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

The study identified 12 potential biomarkers for hair loss and how they affect hair growth.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.