Carbonylation of Hair Proteins: A Robust Biomarker of Molecular and Structural Oxidative Damage in Hair Fibers

February 2025 in “ International Journal of Cosmetic Science ”

Camille Grosjacques, Sabine Babiel, Jing Hodes, Anaïs Bobier, Andrea Cavagnino, Martín A. Baraibar

protein carbonylation cysteic acid oxidative damage photochemical oxidation melanin proline threonine arginine lysine peptide bonds

This study investigates the use of protein carbonylation as a biomarker for oxidative damage in hair, comparing it with cysteic acid. Both markers increase with chemical and photochemical oxidation, correlating with decreased physical properties like tensile strength. Protein carbonylation is particularly effective for tracking photochemical oxidation, offering advantages over cysteic acid due to its sensitivity and ability to visualize damage in situ. The study confirms that melanin provides a photoprotective effect, and identifies additional oxidation targets such as proline, threonine, arginine, lysine, and peptide bonds.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

research Carbonylation of Hair Proteins: A Robust Biomarker of Molecular and Structural Oxidative Damage in Hair Fibers

February 2025 in “International Journal of Cosmetic Science”

research Protein Carbonylation As A Reliable Read-Out Of Urban Pollution Damage/Protection Of Hair Fibers

September 2022 in “Cosmetics”

research Vibrational Raman and IR Data on Brown Hair Subjected to Bleaching

3 citations, September 2021 in “Data in brief”

Bleaching hair changes its structure and weakens it, which is important for understanding hair damage and creating treatments.

research Photochemical Alterations in Human Hair: Artificial Irradiation and Investigations of Hair Proteins

27 citations, January 1995

Melanin in black hair protects it from sun damage better than light-brown hair.

research Cuticle Damage and the Tensile Properties of Human Hair

27 citations, February 1991

Cuticle damage doesn't affect hair's tensile strength; the cortex is responsible for it.

Similar Research

5 / 1000+ results

The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review

research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review

1 citations, July 2023 in “Frontiers in Immunology”

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Advances in Chitosan-Based Nanoparticles for Drug Delivery

Carbonylation of Hair Proteins: A Robust Biomarker of Molecular and Structural Oxidative Damage in Hair Fibers

Research cited in this study

research Carbonylation of Hair Proteins: A Robust Biomarker of Molecular and Structural Oxidative Damage in Hair Fibers

research Protein Carbonylation As A Reliable Read-Out Of Urban Pollution Damage/Protection Of Hair Fibers

research Vibrational Raman and IR Data on Brown Hair Subjected to Bleaching

research Photochemical Alterations in Human Hair: Artificial Irradiation and Investigations of Hair Proteins

research Cuticle Damage and the Tensile Properties of Human Hair

Related Community Posts Join

community Vegan Protein Powder Make Loss Worse?

community Does whey protein and creatine aggravate hair loss?

community Can Soy Protein slowing down baldness?

community The Korean began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor)

community Just sharing my holy grails. I have SO many baby hairs. I suffered with telogen effluvium and personally adding in a protein shake a day helped tremendously, I didn’t realize how packed full of vitamins they were. I used TOPICAL minox and had an elevated heart rate

community Great news recently for people with hairloss!

Similar Research

research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review

research Advances in Chitosan-Based Nanoparticles for Drug Delivery

research Protein Carbonylation As A Reliable Read-Out Of Urban Pollution Damage/Protection Of Hair Fibers

research Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use

research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome