TLDR Protein carbonylation is a sensitive marker for oxidative damage in hair, especially from light exposure.
This study investigates the use of protein carbonylation as a biomarker for oxidative damage in hair, comparing it with cysteic acid. Both markers increase with chemical and photochemical oxidation, correlating with decreased physical properties like tensile strength. Protein carbonylation is particularly effective for tracking photochemical oxidation, offering advantages over cysteic acid due to its sensitivity and ability to visualize damage in situ. The study confirms that melanin provides a photoprotective effect, and identifies additional oxidation targets such as proline, threonine, arginine, lysine, and peptide bonds.
February 2025 in “International Journal of Cosmetic Science” Protein carbonylation is a sensitive marker for oxidative damage in hair, especially from light exposure.
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