16 citations
,
September 2008 in “Dermatologic Therapy” This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.
16 citations
,
December 2007 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the impact of polycystic ovary syndrome on health-related quality of life, highlighting its negative effects which may be influenced by cultural perceptions, obesity, infertility, and menstrual issues.
16 citations
,
July 2007 in “Facial Plastic Surgery Clinics of North America” This article reviews approaches to facial aging in Asian patients, discussing cultural perspectives and proposing a new paradigm of youthful appearance, but provides no new clinical results.
16 citations
,
April 2007 in “Journal of Medical Primatology” This study reports that a 14-year-old female rhesus monkey with alopecia universalis was found to have a T-cell-mediated autoimmune disease similar to human alopecia areata universalis.
15 citations
,
August 2022 in “Journal of endocrinological investigation” This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.
15 citations
,
February 2021 in “Scientific Reports” This study found that novel RNA aptamers specifically inhibited FGF5-induced cell proliferation, suggesting their potential as candidates for treating FGF5-related diseases or hair disorders.
15 citations
,
June 2018 in “Life Sciences” This study found that Diabetex significantly improved wound healing and reduced fasting blood sugar in diabetic rats, showing potential as a safe and economic treatment strategy for diabetic-resistant wounds.
15 citations
,
November 2017 in “Drug Development and Industrial Pharmacy” This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.
15 citations
,
January 2008 in “Annales de Toxicologie Analytique” This study concluded that standard decontamination procedures do not fully remove external contamination from post mortem hair specimens, which complicates using hair analysis to assess long-term drug exposure.
15 citations
,
December 2007 in “Dermatologic Therapy” This review discusses past hair transplantation techniques for androgenic alopecia and current research to improve results, but it reports no new clinical outcomes.
15 citations
,
November 2006 in “Journal of Pharmaceutical and Biomedical Analysis” This study developed and validated a reliable method to measure finasteride levels in human plasma, which was successfully used to assess its pharmacokinetics after a 5 mg dose in healthy volunteers.
15 citations
,
October 2003 in “Dermatologic Surgery” This study found that combining drug therapy with hair grafts can regress male androgenetic alopecia from Hamilton type V to type III.
14 citations
,
January 2025 in “AAPS PharmSciTech” This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
14 citations
,
July 2017 in “Monatshefte für Chemie - Chemical Monthly” This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.
14 citations
,
March 2016 in “Cutaneous and Ocular Toxicology” This study observed that SC users commonly exhibited dermatological findings like periorbital darkening and blade scars, highlighting the importance for dermatologists to recognize these markers for early diagnosis and intervention.
14 citations
,
November 2015 in “Annals of the New York Academy of Sciences” This review discusses dietary manipulation strategies in a mouse model of CBS deficiency and reports no new results; the authors emphasize the importance of understanding gene-diet interactions.
14 citations
,
June 1952 in “The BMJ” Phenobarbitone can cause severe and sometimes fatal skin reactions.
13 citations
,
March 2020 in “Frontiers in cell and developmental biology” This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.
13 citations
,
February 2018 in “Bio-medical Materials and Engineering” This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
13 citations
,
May 2016 in “International journal of biological macromolecules” This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.
13 citations
,
November 2014 in “Clinics in Plastic Surgery” This article reviews the use of the transtemporal approach for midface and lower eyelid-cheek junction rejuvenation, detailing surgical techniques, post-operative care, and potential complications, but reports no new clinical results.
13 citations
,
March 1998 in “Journal of Biomedical Materials Research” This study found that island grafting in guinea pigs enabled the isolated study of early skin regeneration processes, distinguishing them from natural wound closure mechanisms like epithelialization and contraction.
13 citations
,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
13 citations
,
January 1963 in “Radiation Research” This study observed that in mice, small-scale x-ray irradiation resulted in uniquely rapid healing of hair follicles, differing from the hypertrophic and hyperplastic responses seen in larger irradiated areas.
12 citations
,
April 2025 in “Discover Pharmaceutical Sciences” This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.
12 citations
,
September 2021 in “Stem Cell Reviews and Reports” This study suggests that StemMACS MSC Expansion Media is more suitable than PowerStem MSC1 media for expanding therapeutic adipose-derived mesenchymal stem cells, with less expression of negative markers and better chromosomal stability.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.