Androgenetic Alopecia: Combining Medical and Surgical Treatments

October 2003 in “ Dermatologic Surgery ”

Pierre Bouhanna

androgenetic alopecia minoxidil finasteride microtransplantation hair follicles 5α-reductase Dynamic Multifactorial Classification Rogaine Propecia

From the encyclopedia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Studysummary This study found that combining drug therapy with hair grafts can regress male androgenetic alopecia from Hamilton type V to type III. Our plain-language summary of this paper — not a Tressless recommendation.

This 19-year-old document discusses the use of medical and surgical treatments for androgenetic alopecia, including the drugs minoxidil and finasteride, as well as microtransplantation of hair follicles. The article suggests combining drug treatment with hair transplantation for optimal results. The document also explains the pathophysiology of androgenetic alopecia and the role of the androgenic enzyme 5α-reductase in hair loss. The article concludes that investigative methods and the Dynamic Multifactorial Classification can make it easier for patients to follow treatment results.

View this study on journals.lww.com →

Discuss this study in the Community →

Research cited in this study

9 / 9 results

research Multifactorial Classification of Male and Female Androgenetic Alopecia

32 citations , June 2000 in “Dermatologic Surgery”

Different factors help diagnose and treat hair loss accurately.

Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

115 citations , November 1999 in “Journal of The American Academy of Dermatology”

In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.

research Management of Androgenetic Alopecia

40 citations , May 1999 in “Journal of The European Academy of Dermatology and Venereology”

This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations , September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Androgenetic Alopecia: An Autosomal Dominant Disorder

80 citations , January 1995 in “The American Journal of Medicine”

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

40 citations , February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Taking finasteride pills and using minoxidil lotion together can help grow hair.

research Topical Minoxidil Used Before and After Hair Transplantation

27 citations , January 1989 in “The Journal of dermatologic surgery and oncology”

This study found that using 2% topical minoxidil before and after hair transplantation may improve graft outcomes by reducing initial shedding in patients with androgenetic alopecia.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations , September 1977 in “British Journal of Dermatology”

This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.