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This study found that anagen stage protein homogenates and specific epitopes from melanogenesis proteins activated CD8 T cells, suggesting alopecia areata is an anagen-specific disease.

This study suggests that pilomatrixomas' maturation towards areas of shadow cells is linked to a gradual loss of differentiation-specific hair keratins, supporting a hair matrix origin for the tumor.

This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.

This study found that early pigment cell markers Sox10 and c-KIT, as well as DCT/TRP-2, were detectable in melanogenically-active melanocytes of the anagen bulb in human hair follicles.

This study investigated alkaline phosphatase activity in scalp biopsies from patients with alopecia areata and totalis, but provides no new conclusive clinical results.

This study suggests that different melanocyte subpopulations in hair follicles have varying patterns of apoptosis and survival during the catagen phase, which may inform models for modulating melanocyte behavior in vivo.

This study indicates that the OVOL1-OVOL2 axis may play a significant role in hair follicle differentiation and growth, potentially serving as therapeutic targets for hair disorders like alopecia and in the tumorigenesis of pilomatricoma.

This study found that nuclear beta-catenin, LEF1, and PHLDA1 expression was conserved in matrical tumors, suggesting a shared tumorigenesis process involving Wnt pathway activation.

This case report introduces 'onycholemmal carcinoma' as a designation for a slowly growing malignant tumor of the nail bed epithelium in a 69-year-old male, with no recurrence or metastasis observed over four years after treatment.

In this study, the staining properties of two types of cysts, epidermal and pilar, were found to differ, supporting their origins from the epidermis and the trichilemmal hair follicle layer, respectively.

This review explores the multifaceted roles of melanocytes in skin biology, emphasizing their potential impact on future research to prevent and treat skin diseases, but reports no new experimental results.

This case report describes a pilomatricoma in a 21-year-old woman, highlighting the diagnostic process and illustrating the potential for intraoral surgical access to minimize scarring.

This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.

This study observed two cases of pigmented epithelioid melanocytoma suggesting potential differing origins: one from a hair follicle's outer root sheath and another from an intradermal nevus.

This study identified a new 65 kD and 48 kD keratin pair expressed in specific mouse epithelial sites, suggesting a unique evolutionary branch of hair-related keratins.

In this study, all-trans retinoic acid was found to promote differentiation and inhibit proliferation of amelanotic melanocytes from human hair follicles, suggesting a potential role in melanogenesis.

This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.

In this study, researchers identified two de novo germline missense mutations in the hair keratins hHb1 and hHb6 in patients with monilethrix whose parents were not clinically affected.

This study found that in mice, deleting the keratin 10 gene enhances sebocyte differentiation and increases secretion of sebum and certain lipids without affecting proliferation-associated keratins.

This report describes a unique benign neoplasm on the nail unit called onychoblastoma, which histologically resembles a trichoblastoma, marking the first documented case of this tumor type.

This study describes the structure and composition of the epidermal horny layer in elephant seals, noting that its keratinized cells are attached without a specialized fission zone, differing from the sloughing mechanism in reptiles.

This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.

This study found no conclusive link between prolonged mibolerone treatment and perifollicular mineralization in toy poodles, suggesting it may instead be a senile change common in the breed.

This study found that human skin melanocytes with low mutation burdens are smaller, less dendritic, and exhibit stem-like features, often residing in UV-protected hair follicles, suggesting their role in replenishing sun-damaged epidermis.

This study developed a novel monoclonal antibody, TYHF-1, which specifically reacts with hair keratins but not with epidermal keratins or various other tissue cells.

This study found a decreased number of follicular melanocytes in patients with alopecia areata, though it remains unclear if this decrease is due to autoimmune attack or rapid hair cycling.

This study found that pilomatricomas exhibit co-expression of hair keratin hHa5 and HOXC13 in lower transitional cells, but lack LEF1 and β-catenin co-expression necessary for canonical Wnt signaling pathway-controlled cortical differentiation.

This study identified a monoclonal antibody, HKN-2, that recognizes specific cells in human skin and may indicate a common antigenic determinant between hair and other skin epithelial tissues.

This article explores the use of monoclonal antibodies to study the presence and distribution patterns of melanocytes in developing human skin, but reports no new clinical results.