Expression of Type I Hair Keratins in Follicular Tumors

    B. Cribier, Bernard Peltre, Lutz Langbein … E Grosshans
    Studysummary This study suggests that pilomatrixomas' maturation towards areas of shadow cells is linked to a gradual loss of differentiation-specific hair keratins, supporting a hair matrix origin for the tumor.
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    Research cited in this study 11

    1. Immunohistochemical Localization of Cytokeratins and Involucrin in Calcifying Epithelioma: Comparative Studies with Normal Skin British Journal of Dermatology · 2006
    2. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    3. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    4. Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype Journal of Investigative Dermatology · 1999
    5. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    6. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    7. Spiny Keratoderma: A Demonstration of Hair Keratin and Hair Type Keratinization Journal of Cutaneous Pathology · 1999
    8. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    9. Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes Journal of biological chemistry/˜The œJournal of biological chemistry · 1998
    10. Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix Nature Genetics · 1997
    11. Sequence Data and Chromosomal Localization of Human Type I and Type II Hair Keratin Genes Experimental Cell Research · 1995

    Related research 2

    1. Expression of Type I Hair Keratins in Follicular Tumors British Journal of Dermatology · 2001
    2. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989