Onychoblastoma – Hamartoma of the Nail Unit: A New Entity?

    January 2005 in “ Journal of Cutaneous Pathology
    Cosimo Misciali, Píer Alessandro Fanti, Matilde Iorizzo, Bianca Maria Piraccini, Antonellá Tosti
    TLDR A new benign nail tumor called onychoblastoma was identified.
    The document described a case study of a 50-year-old Peruvian man with a subungual verrucous mass on his toe, which was identified as a new type of benign neoplasm named onychoblastoma. This tumor exhibited histological features similar to trichoblastoma, a neoplasm with follicular differentiation, and was characterized by nodular structures resembling follicular infundibulum and germ-like aggregations. The study highlighted the similarities between hair follicles and nail units, suggesting a common embryological origin. The differential diagnosis considered basal cell carcinoma, but the unique histological aspects of onychoblastoma distinguished it as a separate entity.
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