TLDR Alkaline phosphatase activity decreases in early alopecia areata.
The study investigates the role of alkaline phosphatase (A.P.) in alopecia areata and alopecia totalis by analyzing 10 scalp biopsies from patients at different stages of hair loss and regrowth. Previous reports indicated a decrease in A.P. activity in hair papillae during early alopecia areata. This research aims to further understand A.P. activity in these conditions, including areas treated with hydrocortisone injections. The precise role of A.P. in cutaneous metabolic processes remains unclear, but its activity is linked to various biochemical processes and may influence hair loss and regrowth.
73 citations
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July 1956 in “Journal of Investigative Dermatology” Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.
521 citations
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January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
1 citations
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January 2022 in “Dermatology Reports” Many people with hair loss, especially those with telogen effluvium and alopecia areata, often have a sensitive scalp.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.
September 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Rosemary is as effective as Minoxidil for treating alopecia areata.
109 citations
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May 2011 in “Dermatologic Therapy” Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.
