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750-780 / 1000+ results![Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles](/images/research/104cf6c2-d495-4bfd-b9fe-dc77d7c18662/small/2216.jpg)
research Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles
Finasteride potentially treats hair loss by reducing DHT production.
![Getting to the Core of the Dermal Papilla](/images/research/3ae74d13-f7d6-4843-8936-ebbcd66f925e/small/13878.jpg)
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
![Biology of Hair Growth](/images/research/f2cb7a0a-c3d8-463a-ad19-79c4dad85088/small/21200.jpg)
research Biology of Hair Growth
Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
![Diagnosis and treatments of hirsutism: where are we?](/images/research/f65116dd-01af-43ae-bc3a-880ee859132d/small/14815.jpg)
research Diagnosis and treatments of hirsutism: where are we?
Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
![The childbearing years: hair diseases](/images/research/207f1b07-c73e-4568-8c64-5abe578f51ae/small/23450.jpg)
research The childbearing years: hair diseases
Different hair diseases affect people during childbearing years, with treatments ranging from medication to psychological support.
![Telogen Effluvium](/images/research/36f5c565-805c-48cf-a90d-199e1c16eb7e/small/24843.jpg)
research Telogen Effluvium
Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
![Colorimetry provides a rapid objective measurement of <i>de novo</i> hair growth rate in mice](/images/research/d1dd78c1-dc03-4f4a-9d37-79ee21fbe72c/small/32548.jpg)
research Colorimetry provides a rapid objective measurement of de novo hair growth rate in mice
Colorimetry can accurately measure hair growth rates in mice.
![Dermal papilla regulation of hair growth and pigmentation](/images/research/34ff9d11-2b8f-45a9-805b-5bb7ce68f6aa/small/17776.jpg)
research Dermal papilla regulation of hair growth and pigmentation
Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
![[Androgenic alopecia revealing an androgen secreting ovarian tumor].](/images/research/d5300220-943a-4f8f-9e95-9759c55a3d5d/small/12343.jpg)
research [Androgenic alopecia revealing an androgen secreting ovarian tumor].
An 80-year-old woman's severe hair loss was caused by a hormone-secreting ovarian tumor.
![Androgen Receptor–Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia](/images/research/3fc24651-e4ea-4a26-92c9-a65dd4be6bec/small/5523.jpg)
research Androgen Receptor–Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia
Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
![Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia](/images/research/7612e2ed-4985-47f0-9575-d8b838a64009/small/3314.jpg)
research Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia
Women with hair loss have more androgen receptors in certain hair follicles.
![A missense mutation in Lama3 causes androgen alopecia](/images/research/13aba7c7-e53b-4dde-b6b4-a35a97279433/small/16398.jpg)
research A missense mutation in Lama3 causes androgen alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
![Up-regulation of androgen receptor by heat shock protein 27 and miR-1 induces pathogenesis of androgenic alopecia.](/images/research/8b41167c-92b1-4dcd-b984-3895c23d8370/small/5572.jpg)
research Up-regulation of androgen receptor by heat shock protein 27 and miR-1 induces pathogenesis of androgenic alopecia.
Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.
research Female androgenetic alopecia with male pattern caused by an androgen-producing tumor
![Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families](/images/research/ca64b393-ca48-4c14-84a3-c015aa8ab4fa/small/3684.jpg)
research Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families
No clear link between specific gene and hair loss in Mexican brothers.
![Investigation of follicle stimulating effect of medical cosmetic remedies on the androgen alopecia model in rats](/images/research/75744af1-ac8c-49da-8c65-ea3d788adc90/small/13386.jpg)
research Investigation of follicle stimulating effect of medical cosmetic remedies on the androgen alopecia model in rats
The cream-mask and gel-mask with certain plant extracts improved hair growth in rats similar to a common hair growth treatment.
research Unrevealing the Potential of Sansevieria trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis, and In-Silico Studies
![Urinary steroids in men with male-pattern alopecia](/images/research/f850ca9f-8002-4614-a0f0-16de70138a80/small/15427.jpg)
research Urinary steroids in men with male-pattern alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
![COVID‐19, androgens, and androgenic alopecia](/images/research/7cdb95b0-39e1-47c8-aa88-c65ea51899aa/small/5243.jpg)
research COVID‐19, androgens, and androgenic alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
![Effect of age and gender on alopecia in patients hospitalized with COVID-19](/images/research/630d6e0b-436f-440e-acd9-dd89a5ee814b/small/23580.jpg)
research Effect of age and gender on alopecia in patients hospitalized with COVID-19
Older male COVID-19 patients are more likely to experience hair loss.
![[Androgenetic alopecia].](/images/research/0e447c2a-9093-4393-b321-b7b5f7ff34f6/small/2411.jpg)
research [Androgenetic alopecia].
Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.
![The role of androgen and androgen receptor in skin-related disorders](/images/research/a5b97905-8ea3-46f1-b909-2d0739393c0c/small/16257.jpg)
research The role of androgen and androgen receptor in skin-related disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
![Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells](/images/research/a48557bd-260b-4246-86fd-b2bef9893588/small/26110.jpg)
research Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells
TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
![Androgens/Androgen Receptor in the Management of Skin Diseases](/images/research/e88f3f96-57dc-422a-9978-20bb405ba9b2/small/15764.jpg)
research Androgens/Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
![Androgens and androgen receptor action in skin and hair follicles](/images/research/5cf183ae-90fc-4f0b-b922-b3b64689b16f/small/15994.jpg)
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
![Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways](/images/research/76616d31-225f-46cb-b6fb-1d3cb363a7ed/small/4037.jpg)
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
![Androgen effects on the skin](/images/research/22b50022-4e1a-4593-86b1-508561f7ca96/small/18638.jpg)
research Androgen effects on the skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
![Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep](/images/research/81a4efff-ef82-4986-9af6-241a1aae4491/small/17465.jpg)
research Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep
Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
![Androgenetic alopecia](/images/research/0fc7c99f-ae49-43d0-95e2-a0722a3d31e2/small/2231.jpg)
research Androgenetic alopecia
Hair loss from genetics and hormones can be treated with drugs or surgery.