This study examined the relationship between sympathetic nerve endings and alopecia using direct and indirect immunofluorescence on human tissue samples, reporting no new clinical results.
4 citations
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May 2013 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study reported that Gagamchengyoung-tang may reduce scalp disorder and increase hair density in alopecia patients with a febrile tendency.
November 2025 in “Skin Health and Disease” This study found that patients with alopecia areata had a higher prevalence of depression, anxiety, and alexithymia compared to normative data, with alexithymia more common in those with earlier onset AA, lower education levels, and younger age.
March 2026 in “Portuguese Journal of Dermatology and Venereology” This study found that patients with androgenetic alopecia and alopecia areata experienced a significant impact on quality of life, with moderate levels of anxiety and depression, and no significant difference in psychiatric comorbidities between the groups.
61 citations
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September 2011 in “Pain” This study observed that N-palmitoylethanolamine (PEA) may relieve pain by enhancing de novo neurosteroid synthesis, evidenced by increased allopregnanolone levels and protein expression in pain models, dependent on PPAR-α.
15 citations
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July 1997 in “Clinics in Dermatology” Traditional Chinese medications can cause skin reactions, and better testing and reporting are needed to identify allergens.
9 citations
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November 2022 in “Journal of Cosmetic Dermatology” Among patients treated at Thomas Jefferson University, this study found that adding cryotherapy to intralesional triamcinolone acetonide (IL TAC) was more effective at reducing keloid size compared to IL TAC alone, although both treatments similarly eased pruritus and pain.
July 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin may help treat male pattern baldness.
In this study involving two volunteers with Androgenetic Alopecia, phototherapy using red and blue wavelengths promoted benefits, as observed through photographic and trichoscopy comparison after 12 weekly sessions.
8 citations
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December 2015 in “Daehan han'yi hag'hoeji/Journal of Korean medicine” This study found that transtherapy, a treatment using Korean medicine, significantly improved acne scars, reducing the scarring grade from an average of 3.5 to 1.5 in moderate and severe cases.
1 citations
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September 2021 in “Dermatologic Therapy” The researchers reported that intralesional botulinum toxin A effectively alleviated pain associated with cutaneous leiomyomas in a patient with hereditary leiomyomatosis and renal cell cancer syndrome, with repeated treatments every three months maintaining pain relief over 1.5 years.
12 citations
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December 2018 in “Dermatologic Therapy” Small Botox dose effectively treats hair loss in Chinese men.
January 2025 in “Journal of Clinical Personalized Medicine” This study reviewed literature on traditional Chinese medicine external therapies for alopecia, finding them effective across various types, with combined internal and external approaches showing better results; however, concerns about the rigor and precision of current research highlight a need for further study.
May 2026 in “Malahayati Nursing Journal” In this study, a single alopecia patient receiving acupuncture therapy for six weeks displayed gradual improvements, including reduced hair loss, better scalp condition, and enhanced comfort and sleep, suggesting acupuncture may be a safe complementary treatment option for alopecia management.
41 citations
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March 2010 in “Psychology Research and Behavior Management” This review discusses the complex interplay between the nervous system and skin conditions, highlighting various treatment strategies, but reports no new research findings.
29 citations
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January 2023 in “Journal of Clinical Medicine” This review discusses psychological treatments for alopecia, finding limited but positive effects on mental health, quality of life, and possibly hair growth; however, more research is needed to establish intervention efficacy.
This study of patients with moderate to severe alopecia areata in Morocco found that oral betamethasone mini-pulses yielded ≥50% hair regrowth in 62.5% of cases, improved quality of life scores, and were generally well-tolerated, though relapses and mild side effects were noted.
8 citations
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September 2021 in “Skin appendage disorders” This review discusses trichotillomania, including its diagnosis and management, and emphasizes the importance of a psychiatry-dermatology liaison alongside behavioral therapy and pharmacological options.
December 2023 in “PubMed” This study highlights that homemade topical herbal preparations, although popular for their perceived safety, may lead to allergic reactions, notably with Mediterranean herbs, and advises cautious use, particularly for allergy-prone individuals.
August 2018 in “Cadernos de Agroecologia” This study reported that a new sulfur paste formulation with added plant extract and propolis effectively treated scabies in rabbits by promoting rapid tissue regeneration, hair growth, and eliminating secondary infections, offering a more affordable and less irritating alternative to commercial treatments.
This study evaluated the use of dutasteride mesotherapy for treating androgenetic alopecia in real clinical practice, finding it effective in improving hair loss for both men and women with mild side effects, primarily pain.
March 2026 in “Journal of the American Academy of Dermatology” This clinical review evaluates current evidence on various adjunctive therapies for androgenetic alopecia, highlighting modest benefits for some interventions but emphasizing significant gaps and the need for rigorous, high-quality research to guide effective management strategies.
This case report describes a 61-year-old man with long-standing alopecia areata who experienced complete hair regrowth following nine months of acupuncture therapy, suggesting potential efficacy for this non-pharmacological treatment in managing the condition.
January 2004 in “Side effects of drugs annual” Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
21 citations
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August 2011 in “Body Image” This study found that acceptance of hair loss is associated with lower psychological distress in young men, highlighting its adaptive role compared to compensation and avoidance strategies.
In this study, calcium imaging in transgenic mice revealed that non-neuronal TRPV4 in the skin enhances afferent signaling during electrical stimulation, suggesting a role for neuroimmune interaction in acupuncture signal initiation.
1 citations
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December 2017 in “Hygeia - Revista Brasileira de Geografia Médica e da Saúde” This study discusses potential connections between geography, stress, and alopecia areata, suggesting that stress is a key factor influencing the condition, alongside geographic factors.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review examines the potential of various medicinal herbs, such as Ginkgo biloba and Rosmarinus officinalis, as alternative or complementary therapies for alopecia, highlighting their diverse mechanisms like enhancing scalp health and inhibiting DHT, while calling for further scientific validation of their efficacy.
June 2023 in “British Journal of Dermatology” In this study, researchers evaluated online resources for psychological support for alopecia areata patients and found the quality lacking, with most resources not providing adequate advice or referring to therapies like cognitive behavioral therapy, despite the significant psychological impact of the condition.