TLDR Botulinum toxin injections effectively relieve pain from cutaneous leiomyomas.
The document reported a case of a 36-year-old male with hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC) who had multiple painful cutaneous leiomyomas. Traditional treatments were ineffective, so intralesional botulinum toxin A (BTA) injections were administered, providing immediate pain relief and maintaining efficacy over repeated treatments every 3 months for 1.5 years. The study concluded that intralesional BTA is a safe and effective alternative for managing pain in cutaneous leiomyomas, especially when surgery is not viable due to lesion extent or aesthetic concerns.
44 citations,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
36 citations,
January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
44 citations,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
8 citations,
August 2018 in “International Journal of Dermatology” The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.