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research Acute Diffuse and Total Alopecia of the Female Scalp: A New Subtype of Diffuse Alopecia areata That Has a Favorable Prognosis – A Reply
This study suggests a new subtype of alopecia, termed 'acute diffuse and total alopecia of the female scalp' (ADTAFS), characterized by acute and total hair loss in women with a favorable recovery profile.
research Alopecic and Aseptic Nodules of the Scalp/Pseudocyst of the Scalp: Clinicopathological and Therapeutic Analyses in 11 Korean Patients
This study observed inflammatory and granulomatous infiltration in alopecic nodules of the scalp and suggested that AANS should be considered in diagnoses of alopecic nodules.
research Acquired Progressive Kinking of the Hair
This discussion suggests that acquired progressive kinking of hair in androgen-dependent scalp areas may indicate the early stages of androgenetic alopecia with a poor prognosis, but it offers no new clinical findings.
research Akkermansia muciniphila promotes testosterone‐mediated hair growth inhibition in mice
This study investigated the effects of Akkermansia muciniphila on testosterone-induced hair growth inhibition in mice, finding that both live and pasteurized forms significantly encouraged hair growth and increased hair follicle size and growth factor levels compared to testosterone treatment alone.
research BH19 ‘JAK in the box?’ Long-term safety concerns with oral Janus kinase inhibitors for alopecia areata
This study reviewed clinical trials on JAK inhibitors for alopecia areata, finding them effective for short-term hair regrowth with a favorable safety profile, but noted limited data on long-term risks like malignancies or cardiovascular events beyond two years.
research A Review of JAK Inhibitors for Treatment of Alopecia Areata in the Military Health Care System
This review explored treatment options for alopecia areata in the military health care system, evaluating the pathogenesis and impact of the condition as well as the efficacy and safety of FDA-approved JAK inhibitors, baricitinib and ritlecitinib.
research Signal Detection for Adverse Events of Finasteride Using Korea Adverse Event Reporting System (KAERS) Database
research 26 Characterization of a murine model of aa induced by adoptive transfer of cultured lymph node cells
In this study, researchers used a mouse model of alopecia areata to demonstrate that both ruxolitinib and baricitinib, oral JAK inhibitors, reduced hair loss, CD8+ cell infiltration, and expression of disease-related markers, with baricitinib showing greater effectiveness.
research Acne Keloidalis Nuchae
This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.
research Drug-Induced Alopecia Areata From Upadacitinib
In this case report, a 55-year-old woman developed alopecia areata approximately one year into her treatment with upadacitinib for atopic dermatitis, raising questions about a potential drug-induced link that has not been reported before.
research Alopecia areata incognito: A rare cause of hair loss in children
Alopecia areata incognito in children can be effectively treated with triamcinolone acetonide and supplements, leading to full hair regrowth.
research Alopecia areata
This review highlights the variability and unpredictability of alopecia areata, ranging from single scalp patches to total body hair loss, and notes the 2022 approval of the first AA-specific drug, baricitinib, potentially spurring new research into targeted treatments.
research 0527 Effectiveness of janus kinase inhibitor for rapidly progressive acute alopecia areata
Baricitinib effectively stops hair loss and promotes regrowth in acute alopecia areata.
research A protein kinase target of a PDK1 signalling pathway is involved in root hair growth in Arabidopsis
AGC2-1 protein is essential for root hair growth in Arabidopsis.
research Treatment of alopecia areata with the janus kinase inhibitor upadacitinib: A retrospective cohort study
This article addresses the pathogenesis of alopecia areata and discusses the emerging role of oral and topical JAK inhibitors in its treatment, but reports no new clinical findings.
research Identification of compound heterozygous mutations in AP1B1 leading to the newly described recessive keratitis–ichthyosis–deafness (KIDAR) syndrome
This report describes a new case of syndromic ichthyosis caused by compound heterozygous mutations in AP1B1, detailing the associated clinical features and molecular consequences in the patient.
research Unveiling a Shared Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias
In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
research Aim to alleviate alopecia areata with newly available agents
In this study, the authors discuss that while traditional alopecia areata treatments like corticosteroids offer limited efficacy and pose long-term adverse effects, new treatments using janus kinase inhibitors show potential for changing treatment protocols, pending a better understanding of associated adverse drug events.
research Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway
This review discusses the role of the JAK/STAT pathway in managing alopecia areata and emphasizes the need for further research to determine the ideal JAK inhibitor, as it reports no new clinical results.
research Alopecia Areata in Korea (1982–1994)
This study found that immunotherapy with DNCB or DPCP showed better therapeutic effects than intralesional triamcinolone acetonide for patients with bald areas greater than 50 cm², including alopecia totalis and universalis.
research Efficacy, Safety, and Real-World Aspects of Janus Kinase Inhibitors to Treat Patients With Alopecia Areata
This review discusses the efficacy, safety, and practical aspects of using Janus kinase inhibitors—baricitinib, ritlecitinib, and deuruxolitinib—as treatments for severe alopecia areata in an advanced practice provider context, without reporting specific study results.
research Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride
This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.
research Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata
This study found that adipose-derived stem cells with DKK1 knocked out using CRISPR/Cas9 promoted hair growth in an alopecia areata model more effectively than untreated stem cells, suggesting DKK1 is a potential therapeutic target for this condition.
research Upadacitinib Therapy in Adolescent Severe Alopecia Areata: A Case Series and Narrative Review
Upadacitinib is effective and safe for treating severe Alopecia Areata in adolescents.
research Autoinmune Alopecia/Alopecia Areata
This study outlines treatment strategies for autoimmune alopecia areata, detailing that while mild cases may resolve on their own, severe cases often require intervention, with new JAK inhibitors like baricitinib and ritlecitinib emerging as promising treatments for those not responding to traditional therapies.
research S3886 Concurrent Management of Crohn's Ileitis and Alopecia Universalis With Upadacitinib
This study described a case where both alopecia universalis and Crohn's ileitis in a 23-year-old man showed remarkable improvement with the JAK1 inhibitor upadacitinib, highlighting its potential as a treatment for patients with concurrent conditions.
research The Effectiveness of Forensic Science in the Criminal Justice System - Tasmanian Institute of Law Enforcement Studies (TILES)
This study reports that Korean adolescents with androgenetic alopecia tend to have milder symptoms than adults and a higher prevalence of family history of alopecia.
research Atopic Dermatitis and Multilocular Alopecia Areata Simultaneously Treated With Baricitinib
Baricitinib effectively improved both atopic dermatitis and alopecia areata symptoms in a patient.
research Analisis IMT Terhadap Alopesia Androgenik Fakultas Kedokteran, RS Ibnu Sina Dan Menara UMI Makassar
This study observed an association between body mass index and androgenetic alopecia, with the highest prevalence occurring in individuals with a normal BMI at 34.8%.