TLDR Upadacitinib may cause hair loss.
A 55-year-old woman developed alopecia areata (AA) approximately one year after starting treatment with upadacitinib for atopic dermatitis, as described in this case report. This occurrence suggests a potential link between upadacitinib and drug-induced AA, a connection not previously documented in the literature. The case underscores the need for further investigation into whether upadacitinib can cause AA, highlighting the typical timeline for drug-induced alopecia.
5 citations
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May 2024 in “Journal of Allergy and Clinical Immunology Global” Upadacitinib effectively improved severe atopic dermatitis and alopecia universalis in a 29-year-old man.
March 2024 in “Clinical, cosmetic and investigational dermatology” Upadacitinib may effectively treat alopecia areata without side effects.
3 citations
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May 2023 in “Journal of the American Academy of Dermatology” Certain drugs can cause hair loss, but stopping the drug usually leads to hair regrowth.
3 citations
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March 2023 in “JAAD case reports” Upadacitinib cleared scalp alopecia areata in three patients and also improved atopic dermatitis with minimal side effects.
9 citations
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January 2023 in “Dermatology and therapy” A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.
10 citations
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January 2023 in “SAGE Open Medical Case Reports” Upadacitinib may effectively treat both alopecia universalis and Crohn's disease.
7 citations
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January 2022 in “SAGE open medical case reports” Upadacitinib successfully treated a child's severe skin and hair loss issues.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.