Successful Treatment of Concomitant Alopecia Universalis and Crohn's Disease with Upadacitinib: A Case Report

    January 2023 in “ SAGE Open Medical Case Reports ”
    Leah Johnston, Cathy Lu, Susan Poelman
    Studysummary In this case report, a 23-year-old man with Crohn's disease experienced near-complete resolution of alopecia universalis after 7 months of upadacitinib treatment, suggesting potential benefits for treating concurrent alopecia areata and Crohn's disease.
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    Research cited in this study 10

    1. An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata Frontiers in immunology · 2022
    2. Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib ACG Case Reports Journal · 2021
    3. Gut Instinct: Using Tofacitinib to Treat Alopecia Areata in the Context of Comorbid Inflammatory Bowel Disease JAAD Case Reports · 2020
    4. JAK Inhibition in the Treatment of Alopecia Areata: A Promising New Dawn? Expert review of clinical pharmacology · 2019
    5. Response to Ustekinumab in Three Pediatric Patients with Alopecia Areata Pediatric dermatology · 2018
    6. Effective Use of Ustekinumab in a Patient with Concomitant Psoriasis, Vitiligo, and Alopecia Areata JAAD case reports · 2017
    7. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    8. Alopecia Secondary to Anti-Tumor Necrosis Factor-Alpha Therapy Anais Brasileiros de Dermatologia · 2015
    9. Adalimumab-Induced Psoriatic Alopecia/Alopecia Areata-Like Reaction in a Patient with Crohn's Disease Dermatology Online Journal · 2015
    10. Alopecia Areata in a Patient with Psoriatic Arthritis and Crohn's Disease Receiving Etanercept International Journal of Rheumatic Diseases · 2013

    Related research 5

    1. Real-World Treatment Patterns Among Patients With Alopecia Areata in the USA: A Retrospective Claims Analysis Acta dermato-venereologica · 2023
    2. Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors Journal of autoimmunity · 2022
    3. The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata Journal of Armed Forces Medical College, Bangladesh · 2022
    4. Transient Efficacy of Tofacitinib in Alopecia Areata Universalis Case Reports in Dermatology · 2016
    5. Alopecia Areata Universalis in a Dog Veterinary dermatology · 2015