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research The JAK/STAT signaling pathway: from bench to clinic

489 citations , November 2021 in “Signal Transduction and Targeted Therapy”

This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.

research The role of janus kinases in the treatment of autoimmune skin diseases

1 citations , February 2021 in “Farmacja Polska”

This article reviews the role of the JAK-STAT pathway in inflammatory skin diseases and considers the therapeutic benefits of JAK inhibitors, presenting them as promising treatments but reports no new experimental results.

research Janus kinase (JAK) inhibitors for the treatment of skin and hair disorders: a review of literature

40 citations , December 2016 in “Journal of Dermatological Treatment”

This study reviewed the role of the JAK/STAT signaling pathway in skin diseases and the potential of JAK inhibitors for treating conditions like psoriasis and atopic dermatitis. Although the findings are promising, the authors concluded it is premature to establish their place in dermatological treatments.

research Janus Kinase Inhibitors in Dermatology: Part 1 — General Considerations and Applications in Vitiligo and Alopecia Areata

14 citations , March 2021 in “Actas Dermo-Sifiliográficas”

This review discusses the JAK/STAT signaling pathway's role in immune-mediated skin diseases and examines the efficacy and safety of JAK inhibitors for treating vitiligo and alopecia areata, but reports no new clinical results.

research The Use of Janus Kinase Inhibitors in Alopecia Areata: A Review of the Literature

17 citations , January 2019 in “Journal of cutaneous medicine and surgery”

This review discusses the potential of JAK inhibitors for treating alopecia areata and reports case study evidence of their effectiveness, but formal clinical trials are needed for more definitive conclusions.

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community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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