92 citations
,
January 2012 in “International Journal of Biological Sciences” This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.
100 citations
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November 1997 in “Human Genetics” In this study, researchers found that the prevalent Glu 410 Lys mutation in hHb6 and a new Glu 403 Lys mutation in hHb1 are linked to monilethrix, suggesting a mutational hotspot in type II hair keratins.
578 citations
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May 1996 in “Plant Cell & Environment” This study found that Arabidopsis thaliana plants developed longer root hairs under low phosphorus conditions, suggesting auxin involvement in this adaptive response.
This study revealed that Thai youths who are more worried about androgenetic alopecia tend to experience higher severity of the condition, poorer quality of life, and increased use of multiple hair styling products.
January 2019 in “Applied Organometallic Chemistry” The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.
June 2025 in “British Journal of Dermatology” This study reported significant challenges in the UK care system for alopecia areata patients, including inconsistent care pathways, long waiting times, inadequate access to specialists, and insufficient resources, particularly affecting referral processes and treatment access.
September 2025 in “Journal of Surfactants and Detergents” In this study, shampoos containing sodium lauroyl methylaminopropionate showed superior coacervate formation and lubrication on wet hair, outperforming other amino acid surfactants and suggesting potential for creating low-irritation, high-performance hair products.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
January 2025 in “Regenerative Biomaterials” In this study, a new pH-responsive hydrogel composed of polyvinyl alcohol and boric acid was found to release salvianolic acid B effectively, reducing excessive scar formation and enhancing tissue regeneration during early-stage wound healing.
33 citations
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December 2005 in “Archives of dermatology” This study presents case reports of four patients with alopecia areata or alopecia universalis, highlighting varied responses to treatments like prednisone, intralesional triamcinolone, and squaric acid dibutyl ester.
1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
31 citations
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November 1991 in “Brain Research” Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
April 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” In this study of Beauty and Aesthetics students, researchers found that using a hair tonic made from Green Spinach Leaves significantly reduced hair loss when applied weekly, compared to a control, but no significant difference was observed when increasing application to twice weekly.
January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that type A botulinum toxin treatment significantly increased hair thickness and reduced vellous hair count in patients with androgenetic alopecia, suggesting its potential as an effective therapy.
15 citations
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January 1993 in “DNA sequence” This study sequenced a related gene to KRT2.9 called KRT2.13, which encodes a type II keratin protein not expressed in the hair follicle, and found significant sequence homology suggesting possible gene conversion or conservation of functional sequences.
4 citations
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December 1989 in “The Journal of Dermatology” This study suggests that the amino acid composition of fibrous proteins in normal human hair is similar to that of stratum corneum proteins, particularly in cysteine and glycine content.
January 2025 in “Journal of Dermatology & Dermatologic Surgery” This study reports a unique case of identical twins experiencing alopecia areata at the same time, suggesting potential environmental triggers for this polygenic autoimmune condition.
10 citations
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January 2003 in “Dermatology” This study describes a Japanese family with monilethrix and found no clear genotype/phenotype correlation in cases with the E413K mutation in hHb6.
8 citations
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January 2014 in “Indian Journal of Paediatric Dermatology” This case report describes a 4-year-old boy with congenital alopecia characterized by complete irreversible hair loss and papular lesions associated with keratin-filled cysts.
5 citations
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March 2020 in “Aids Reviews” This review found that hair antiretroviral concentration may be associated with several factors, including hair type and genetic factors, but not with race/ethnicity or alcohol use.
October 2012 in “Institutional Repositories DataBase (IRDB)” The researchers reported that treatment with adipose-derived stem cell conditioned medium significantly increased hair count in the study participants, suggesting it is an effective therapy for hair regeneration.
14 citations
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December 2010 in “Journal of human genetics” This study identified a severe MBTPS2 gene mutation in a Japanese patient with IFAP syndrome, suggesting other factors may influence the varied clinical severity of the condition.
January 2025 in “Dermatologic Therapy” In this study, AA patients and healthy controls showed no significant difference in carotid intima-media thickness, but AA patients had higher diastolic blood pressure and fasting blood glucose levels, indicating potential cardiovascular risks.
7 citations
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January 2011 in “Veterinary Pathology” In this case report, a 9-year-old horse was diagnosed with alopecia areata contributing to Malassezia dermatitis, involving lymphocyte infiltration and symptoms consistent with yeast presence.
5 citations
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January 2018 in “Interdisciplinary sciences: computational life sciences” Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
135 citations
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October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.
12 citations
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January 2014 in “Annals of Dermatology” This study found an association between hydroxyl radical-modified SOD and alopecia areata, suggesting these modifications may lead to antibody induction in the condition.
8 citations
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August 2012 in “Clinical, cosmetic and investigational dermatology” In this study, Doublebase gel was more effective in maintaining and increasing skin hydration compared to Aqueous cream BP, with higher patient satisfaction and preference for future use.
October 2019 in “Journal of Pakistan Association of Dermatologists” This study evaluated azathioprine in treating alopecia areata and found that it was effective for 77.4% of patients, significantly reducing SALT scores after 6 months of treatment, with safety monitored through regular testing.