research Comparison of Androgenic Hormone Levels in Various Phenotypes of Polycystic Ovarian Syndrome in High School Girls Aged 14 to 18 Years
Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.
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research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Reimagining Hair Science: A New Approach to Classify Curly Hair Phenotypes via New Quantitative Geometrical and Structural Mechanical Parameters
New methods to classify curly hair types were developed based on shape and strength.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Aging Skin and Non-Surgical Procedures: A Basic Science Overview
Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Defects in Mitochondrial DNA Replication and Oxidative Damage in Muscle of mtDNA Mutator Mice
Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Intracellular Protons Accelerate Aging and Activate Aging Hallmarks in Mice
Acid inside cells speeds up aging and turns on aging signs in mice.
research Endocrinology of the Aging Prostate: Current Concepts
Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
research Effect of Coffee Berry Extract on Anti-Aging for Skin and Hair: In Vitro Approach
Coffee berry extract may help slow skin aging and prevent hair loss.
research Ocular Manifestations of Hutchinson-Gilford Progeria Syndrome: A Rare Presentation
The report shows a young man with Hutchinson-Gilford Progeria Syndrome had typical and additional eye problems related to the disease.
research Lamins in Development, Tissue Maintenance, and Stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research The Use of Stem Cell Differentiation Stage Factors Taken from Zebrafish Embryos During Organogenesis and Their Role in Regulating Gene Expression of Normal and Pathological Cells
SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
research The Polycystic Ovary Syndrome: A Position Statement from the European Society of Endocrinology
The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Mouse Models with a Disrupted PTHrP Gene or a Disrupted PTH Gene (PTH−/− Mice)
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
research Hopes and Limits of Adipose-Derived Stem Cells and Mesenchymal Stem Cells in Wound Healing
ADSCs help in wound healing and skin regeneration but need more research for full understanding.
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research Age-Related Differences in the Reproductive and Metabolic Implications of Polycystic Ovarian Syndrome: Findings in an Obese, United States Population
Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
research Stress-Related Hair Loss Among the General Population in Al Majma'ah, Saudi Arabia: A Cross-Sectional Study
Stress significantly contributes to hair loss, especially in women and those aged 31-40.
research Expansion of the Spectrum of ITGB6-Related Disorders to Adolescent Alopecia, Dentogingival Abnormalities, and Intellectual Disability
A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
Pro-IGF-II improves muscle repair in old mice.