January 2022 in “Figshare” Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.
January 2021 in “Figshare” Autophagy helps delay aging in mouse glands, maintains fat balance, and controls scent production.
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
May 2019 in “Eurasian Journal of Biosciences” Fenugreek aqueous extract is more effective against acne bacteria than the alcoholic extract.
555 citations,
April 2002 in “The Lancet” Off-pump heart surgery reduces complications without affecting survival rates compared to on-pump surgery.
102 citations,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
58 citations,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
57 citations,
September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
52 citations,
January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
36 citations,
January 2018 in “Burns & Trauma” NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
26 citations,
September 2018 in “Colloids and Surfaces B: Biointerfaces” A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
26 citations,
April 1998 in “Journal of Investigative Dermatology” The study developed a novel in vivo model using transgenic mice to evaluate agents that protect against UVA-induced photoaging. This model used a human elastin promoter linked to a CAT reporter gene to measure elastin gene induction. It showed that PUVA treatment significantly increased promoter activation, which was reduced by sunscreens, particularly those with SPF 15 and UVA filters. The combination sunscreen provided the greatest protection, reducing CAT activity to near baseline levels. This model proved effective for rapidly identifying and comparing compounds that protect against UVA-induced photoaging, despite differences between murine and human skin responses.
22 citations,
February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.
16 citations,
October 2004 in “Journal of Investigative Dermatology” Normal human melanocytes can avoid cell death through multiple pathways.
15 citations,
November 2018 in “Current radiopharmaceuticals” Melatonin can help prevent and treat skin damage caused by gamma rays.
15 citations,
July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
14 citations,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
13 citations,
July 2016 in “Veterinary Dermatology” The study investigated the residual antibacterial activity of canine hairs treated with four different topical antimicrobial sprays against Staphylococcus pseudintermedius. Twelve dogs with no dermatological disease were treated with sprays containing varying concentrations and combinations of chlorhexidine, miconazole, and TrizEDTA. Hairs were collected and tested for bacterial growth inhibition over 10 days. Results showed significant differences in inhibition zones, with spray B (2% miconazole nitrate, 2% chlorhexidine gluconate, TrizEDTA) producing the largest zones, followed by sprays D, C, and A. All sprays maintained antimicrobial activity for 10 days, indicating that the efficacy of these sprays depends on the concentration and combination of active ingredients, which could be beneficial for treating canine pyoderma.
12 citations,
December 1987 in “Cancer Chemotherapy and Pharmacology” Vitamin E in the diet might help protect against hair loss caused by the chemotherapy drug doxorubicin in rabbits.
10 citations,
January 2021 in “Journal of Ginseng Research” Red ginseng oil may help grow hair and protect skin from UVC light.
7 citations,
October 2018 in “South African journal of botany” Clausena anisata may be effective in treating acne due to its ability to fight bacteria, reduce inflammation, and possibly lower sebum production.
6 citations,
March 1984 in “British journal of addiction” The Edwardian medical campaign linked maternal drinking to infant mortality and national decline, influencing hygiene education and leading to a ban on children under 14 from pubs.
5 citations,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
5 citations,
September 2016 in “Journal of Cosmetic Dermatology” Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.
5 citations,
December 2015 in “Dermatologic Therapy” Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.
2 citations,
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride more effective than finasteride for hair growth; SM04554 safe and potentially effective for hair loss.
2 citations,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
1 citations,
December 2022 in “Pharmaceuticals” Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
1 citations,
January 2017 in “Journal of Dermatology and Venereology” The plant extract and minoxidil both reduce hair loss by lowering specific gene expressions.
1 citations,
January 1989 in “Carcinogenesis” The study investigated the effects of dexamethasone (DXME) on mouse skin treated with 12-O-tetradecanoyl-phorbol-13-acetate (TPA). DXME, when applied after TPA, inhibited both the dermal inflammatory reaction and the induction of epidermal ornithine decarboxylase (ODC) activity. During the hyperplastic stage, DXME continued to counteract inflammation but only weakly inhibited ODC induction. Interestingly, in DXME-protected skin, the hyperplastic stage was delayed, and TPA strongly induced ODC activity in the epidermal cell layer before this stage. The study suggested that as the proliferation process was induced, epidermal cells became more sensitive to TPA, potentially becoming less reliant on inflammatory factors for ODC induction.