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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Ethnicity affects how polycystic ovary syndrome shows up in women, with white women having higher metabolic risks but less diabetes, and South Asian women showing more androgenic symptoms and being younger at presentation.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

Androgen affects oil production and hair growth in the skin.

A young girl with high testosterone was thought to have a tumor but actually had PCOS, which was treated with birth control pills.

Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.

Transgender patients on masculinizing hormones have higher hair loss rates than cisgender women.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Adipokines affect skin health and could be targeted for treating skin diseases.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.