April 2020 in “Journal of The American Academy of Dermatology” This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.
May 2015 in “Hair transplant forum international” This article discusses adverse event reporting in clinical trials of finasteride for androgenic alopecia and reports no new clinical findings.
6 citations
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April 2019 in “Endocrinology and Metabolism Clinics of North America” This study observed that testosterone therapy in transgender men enhances both physical and mental health, is safe in the short and middle term with proper follow-up, and highlights the need for endocrinologists to provide gender-affirming care despite its limited presence in medical education.
January 2024 in “Pediatric Dermatology” This case study found that a 9-year-old girl with trichorhinophalangeal syndrome type 1 experienced significant improvements in hair density and length after 4 months of topical minoxidil treatment, suggesting its therapeutic potential for this condition.
13 citations
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September 2018 in “Dermatologic Therapy” This study reports that while topical minoxidil treatment showed a response in less than 40% of men after 24 weeks, oral finasteride stopped hair loss in over 80% of patients at 12 months; perceived sexual side effects of the latter may limit its use.
37 citations
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February 2014 in “Journal of Dermatology” This study found that topical valproic acid significantly increased hair count in male patients with moderate androgenetic alopecia compared to placebo over 24 weeks.
8 citations
,
January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
8 citations
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January 2019 in “Clinical research and trials” This study found that long-term treatment with 1 mg/day finasteride over 10 years resulted in high efficacy and prevention of disease progression in Japanese men with androgenetic alopecia, with no serious adverse reactions reported.
1 citations
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March 2023 in “Frontiers in Medicine” This meta-analysis found that topical prostaglandin analogs could significantly improve hair length and density in patients with hair loss, compared to placebo, without notable safety differences.
August 2026 in “Asclepius International Journal of Scientific Health Science” In this systematic review, dutasteride may be more effective than finasteride for hair growth in men with androgenetic alopecia, but the comparative magnitude of this effect is highly uncertain.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study examines how conditions like PSSD, Long COVID, and ME/CFS form a "Post-Exposure Syndromes" family, initiated by transient exposures but persisting due to complex state-space dynamics, and suggests improving pharmacovigilance to better address and understand these persistent syndromes.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This presentation argues that post-exposure syndromes like PSSD and Long COVID form a coherent group of conditions driven by complex interactions in high-dimensional state spaces rather than singular molecular pathways.
June 2025 in “British Journal of Dermatology” This study reviewed clinical trials on JAK inhibitors for alopecia areata, finding them effective for short-term hair regrowth with a favorable safety profile, but noted limited data on long-term risks like malignancies or cardiovascular events beyond two years.
January 2024 in “Journal of Cosmetic Dermatology” This study reported that the 1565 nm non-ablative fractional laser treatment significantly improved various hair growth indices in patients with androgenetic alopecia compared to 5% minoxidil, demonstrating its superior clinical efficacy and safety for treating this condition.
This study suggests that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens may be potential candidates for use in scalp care cosmetics due to their antioxidative and antimicrobial properties, safety, and favorable user feedback.
August 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review discusses the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil for hair loss but reports no new clinical findings.
407 citations
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January 2008 in “Cochrane Database of Systematic Reviews” This review found that glucocorticoid corticosteroids can improve muscle strength and function in boys with Duchenne muscular dystrophy in the short term, but they are associated with significant short-term adverse effects.
235 citations
,
September 2004 in “The Journal of urology/The journal of urology” This review discusses the role of dihydrotestosterone in benign prostatic hyperplasia and reports no new results; the authors highlight 5alpha-reductase inhibitors as a well-established treatment option.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
46 citations
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May 2009 in “Maturitas” This study found that taking a daily oral dose of 50mg DHEA for one year had no significant impact on blood lipids, insulin sensitivity, or the endometrium in postmenopausal women with low libido.
19 citations
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June 2021 in “The world journal of men's health” This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.
13 citations
,
June 2018 in “Current Urology Reports” This review suggests that while finasteride for male pattern hair loss was previously considered safe, there is now evidence associating 5-α reductase inhibitors with significant sexual and reproductive side effects.
13 citations
,
May 2009 in “Ozone Science and Engineering” This study found that while ozonized olive oil inhibited swelling in a mouse model of hypersensitivity, it also induced inflammatory responses and hair loss with repeated skin application, indicating potential adverse effects.
8 citations
,
October 2022 in “Dermatologic Therapy” In this study, the addition of topical latanoprost to betamethasone treatment improved the therapeutic efficacy for patients with patchy alopecia areata, showing more significant hair regrowth compared to minoxidil alone and enhanced outcomes without adverse effects.
6 citations
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October 2012 in “Pediatrics” This case report describes an 11-year-old girl who experienced hot flashes and menarche after taking a Serenoa repens supplement for telogen effluvium, suggesting a possible but uncertain link between the supplement and hormonal changes.
5 citations
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November 2024 in “Frontiers in Nutrition” In this randomized controlled trial, oral intake of the probiotic Latilactobacillus curvatus LB-P9 significantly improved hair luster, elasticity, and participant satisfaction in individuals with mild to moderate hair damage compared to placebo, without significant adverse effects reported.
5 citations
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November 2023 in “Journal of Feline Medicine and Surgery” This case series reports on five cats who experienced moderate to severe skin reactions after receiving the frunevetmab injection, noting pruritus, alopecia, and ulcerations developing within days of treatment.
5 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
5 citations
,
July 2017 in “Skin appendage disorders” This case report describes a 35-year-old man who developed an atypical DRESS syndrome after taking topiramate for migraine prevention, which resolved with drug withdrawal and symptomatic treatment.
5 citations
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August 2014 in “Australasian journal of dermatology” This article discusses a case of delayed onset perforating folliculitis linked to the use of sorafenib, but it reports no new clinical results.