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Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Prolactin may be important for skin growth and immune function.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

New drugs are improving treatment for hormone-related diseases in small pets.

DA-9401 helps protect rat testis from finasteride damage.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Young women with PCOS without additional risk factors may have normal heart function.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Vitamin D is important for skin health and can help treat and prevent various skin conditions.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.