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Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Oral contraceptives may cause hair loss in women.

PSA can help diagnose high androgen levels in women.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Gene mutations can cause problems in male genital development.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Finasteride-loaded nanoparticles may help treat alopecia.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Testosterone injections can cause skin darkening and thickening.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.