research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
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research A Comparison Between Finasteride, Flutamide, and Finasteride Plus Flutamide Combination in the Treatment of Hirsutism
Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.
research Low-Dose (2.5 mg/Day) Finasteride Treatment in Hirsutism
Low-dose finasteride effectively reduces hirsutism without serious side-effects.
research Phenolsulphotransferase: Localization in Kidney During Human Embryonic and Fetal Development
The enzyme PST is found in developing human kidneys and helps with detoxification and development.
research Itraconazole Therapy for Recalcitrant Dermatophyte Infections
Itraconazole helps improve tough skin infections but may not prevent them from coming back.
research No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors
Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
research Androgenetic Alopecia in a Postmenopausal Woman Due to Ovarian Hyperthecosis
Hair loss in postmenopausal woman caused by ovarian issue.
research Treatment of Hirsutism With Cimetidine: A Prospective Randomized Controlled Trial
Cimetidine did not reduce hair growth in women with hirsutism.
research PCOS: Update and Diagnostic Approach
The document concludes that more research is needed to fully understand the causes of PCOS.
research Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia)
Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.
research Increased Frequency of the DI Genotype of the Angiotensin-I Converting Enzyme and Association of the II Genotype with Insulin Resistance in Polycystic Ovary Syndrome
The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
research Is Prostate-Specific Antigen a Potential New Marker of Androgen Excess in Polycystic Ovary Syndrome?
Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
research Therapeutic Options in Polycystic Ovary Syndrome
The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.
research Immunoregulatory Mechanisms and Stress Hormones in Psoriasis (Part 1)
Stress hormones like cortisol may trigger psoriasis flare-ups.
research The Effect of Anti-Androgens on the Response of Rat Preputial Glands to Testosterone
New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.
research Nutrition of Women with Hair Loss During Menopause
Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
research Menopausal Acne – Challenges And Solutions
Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.
research Increased Risk of Fractures in Patients with Polycystic Ovary Syndrome: A Nationwide Population-Based Retrospective Cohort Study
Women with polycystic ovary syndrome have a higher risk of certain fractures.
research Correlation of Clinical and Biochemical Hyperandrogenism in Thai Women with Polycystic Ovary Syndrome
Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
research Comprehensive Clinical Management of Hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
research Clinico-Investigative Profile of Patients with Hirsutism in a Tertiary Level Institution
Most hirsutism patients had idiopathic hirsutism or PCOS, with hormonal imbalances and signs like acne and irregular periods.
research Isoniazid-Induced Alopecia
Stopping isoniazid can reverse hair loss caused by the drug.
research Urinary Steroids in Men with Male-Pattern Alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia
Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
research An Ovarian Leydig Cell Tumor Undetected by Ultrasound in a Postmenopausal Woman with Hirsutism and Hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research Acne Vulgaris
Oral isotretinoin was recommended for a 21-year-old woman with severe acne.