research Regulation of Adipocyte Dedifferentiation at the Skin Wound Edge
Adipocytes can change into fibroblast-like cells to help with wound healing.
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research Targeted Immunotherapy for Hair Regrowth and Regeneration
Targeted immunotherapy could be a promising new treatment for hair regrowth.
research Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research The Wound Healing of Fractional Photothermolysis Mimics Scarless Healing with Minimal Myofibroblast Activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research The ATP-Dependent Chromatin Remodeler BRG1 Controls Epidermal Keratinocyte Migration During Human Cutaneous Wound Healing
BRG1 is essential for skin cells to move and heal wounds properly.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Abstract Presented at the Joint Meeting of the 21st Meeting of the Japanese Research Society of Clinical Anatomy and the 6th Meeting of the Society for Aging Imaging
High-resolution imaging is crucial for diagnosing and planning treatments in clinical anatomy and aging.
research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research Stabilizing Mutations of KLHL24 Ubiquitin Ligase Cause Loss of Keratin 14 and Human Skin Fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Paraoxonase 1 (PON1) L55M and Q192R Polymorphisms, Lipid Profiles, and Psoriasis
The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.
research Augmentation of HGF Signaling: Potential for Enhancing Hair Follicle Neogenesis and Development in Bioengineered Skin
Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
research Skin Regeneration: Strategies and Innovations
New materials and methods could improve skin healing and reduce scarring.
research Efficacy of Autologous Platelet-Rich Plasma in the Treatment of Male Androgenetic Alopecia
Using your own blood (PRP) can effectively increase hair count and strength in men with hair loss.
research Current and Future Medical Treatment of Androgenetic Alopecia
Treatments for hair loss vary, but cell-based options may be the future.
research Transcriptomics Identifies Potential Novel Therapeutic Targets in Androgenetic Alopecia
Found new possible treatments for hair loss.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Comprehensive Overview of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification
Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.