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Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Stem cell therapy shows promise in improving burn wound healing.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Identified genes linked to male-pattern baldness may help develop new treatments.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.