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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Blocking β-catenin in skin cells improves hair growth during wound healing.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Skin cells can help create early hair-like structures in lab cultures.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Coriander seed oil is safe for healthy adults at up to 600 mg per day.

Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

The document explains various skin conditions in cats and how to diagnose and treat them.